Sinclair Method Studies
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

we will explore some of the potential pitfalls of Sober October, including the Alcohol Deprivation Effect, the dangers of sudden cessation of alcohol, and the neuroscience behind addiction.
The Sunday Reset
Every Sunday, we share a 2-minute insight into the logic of the Sinclair Method.
Join thousands of others for our weekly newsletter and change how you see the problem,
because when you change the way you look at things, the things you look at change.
… There’s a reason we’re called Rethink Drink!
